Sulphasalazine therapy in RA.

Agranulocytosis associated with sulphasalazine therapy.

A case report of a patient with agranulocytosis associated with sulphasalazine therapy is described. Recovery followed supportive therapy and withdrawal of the drug. Investigations including tests for leucocyte antibodies, the presence of which might have suggested an immunological cause for the drug reaction, were negative; an acetylation study, however, characterized the patient as a 'slow' a...

Comparison of corticosteroid and sulphasalazine therapy in ulcerative colitis.

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Sulphasalazine in ankylosing spondylitis.

In recent years sulphasalazine has gained acceptance as an effective agent for the treatment of rheumatoid arthritis. Ankylosing spondylitis is a disease where remission inducing drugs so far have been lacking. In this double blind trial sulphasalazine was compared with placebo in 37 patients with ankylosing spondylitis. Evaluation after three months' treatment showed reduction of inflammatory ...

Combination therapy with methotrexate and sulphasalazine in rheumatoid arthritis--tolerance of therapy.

Sulphasalazine in ulcerative colitis.